Thus, the main goal of the MOFFS project is focused on developing a production scheduling tool using discrete event simulation, priority rules algorithms and iterative optimization algorithms, specifically focused on SMEs with a Make to Order production system. In addition, this innovative tool must be able to carry out rescheduling in real time, in order to cope effectively with the system uncertainty. Scientific studies show that the use of these techniques can generate excellent results. One of the most important efforts will be done to assure that the optimization algorithm will have short computational times for the medium to large problem size problems arising in real-life situations